Abstract Background Lifelong production of the many types of mature blood cells from less differentiated progenitors is a hierarchically ordered process that spans multiple cell divisions.The nature and timing of the molecular events required to integrate the environmental signals, transcription factor activity, epigenetic modifications, and change
PurposeTo assess the non-inferiority of pegfilgrastim versus filgrastim in speeding the recovery of polymorphonuclear cells (PMN) in pediatric patients who underwent autologous peripheral blood stem cell transplant (PBSCT).MethodsThe sample size of this randomized, multicenter, phase III study, was calculated assuming that a single dose of pegfilgr
Abstract The cardiopulmonary system is a physiological cornerstone in the adaptive response to hypobaric hypoxia.Portable devices make it feasible nowadays to precisely assess the response to high altitude (HA) expeditions.In this study, we investigated breathing and arterial blood pressure responses during a Himalayan trek from 665 m to 4,780 m al
A 55-year-old woman, with history of cataract surgery 1 year back, presented with features of ocular inflammation for last 3 months.She had no history of any other intraocular surgery.On examination, anterior segment showed frothy material Hinge in the inferior angle with moderate anterior chamber reaction (cells+/flare+) and sulcus intraocular len
The effect of Ca and Sr-doping on the structural electronic and optical properties Apparel of the cubic Ba1-xCaxTiO3 and Ba1-xSrxTiO3 (x=0.4, 0.6) mixed crystals was investigated using first-principles calculations based on density functional theory (DFT).The calculated band structures based on the optimized geometry of the cell for the solid solut